A chronic, sexually transmitted disease that results from a spirochete of the genus Treponema (T. Pallidum). If left untreated, the disease can cause irreversible damage to the brain, heart, and nervous system leading to rashes, chancres, lesions, papilledema, madarosis, eye inflammation, abducens nerve palsy, oculomotor nerve palsy, conjunctival ulcers, and Argyll-Robertson pupil. It is also congenital and occurs in stages namely, primary, secondary, latent, and tertiary.