A rare, genetic, bilateral, slow-progressing disease affecting the cornea’s stromal layer when discrete crumb-like opacities form in the central anterior stroma in early childhood. These opacities initially appear as subtle fine dots before developing into granules. It is characterized by recurrent corneal erosions causing pain, especially upon waking up or in dry eyes. It is an autosomal dominant inherited disease of the TGFBI gene on the 5q31 locus.
Also Known As
- Corneal Dystrophy Groenouw Type