Aqueous humor is created by the ciliary body or the non-pigmented epithelium in the pars plicata and secreted into the posterior chamber. From the posterior chamber, it flows through the wiry opening between the front of the lens and back of the iris. The aqueous runs off through the pupil into the anterior chamber. It then drains out of the eye through the trabecular meshwork into Schlemm’s canal before ending up in the episcleral veins. The decreased outflow is affected by age, surgery, medication, endocrine factors, glaucoma, trauma, and elevated intraocular pressure.