Usually, yellow spots in your eyes are protein, fat, or calcium growths called pinguecula or fleshy tissue, i.e., pterygium. They don't need treatment unless they interfere with your vision or are bothersome. However, if the white part of your eye appears yellow, it's may be a sign of jaundice. This is a liver disease caused by alcohol abuse, hepatitis, gallstones, and in rare cases, cancer. See an eye specialist immediately.