A very rare syndrome marked mainly by ocular abnormalities, craniofacial dysmorphism, dental defects, hand and foot malformations, various skeletal defects, and mildly delayed mental development. The eye features include microcorneas with of without microphthalmos, fine porous irides, secondary glaucoma, optic atrophy, short palpebral fissures, hypertelorism or hypotelorism, and Adie-Holmes syndrome.