Dorzolamide hydrochloride-timolol maleate ophthalmic solution is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers (failed to achieve target IOP determined after multiple measurements over time).
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https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=b7aa1986-1c24-4733-96b3-e6d8e1d44558&type=display#section-1
